This essay presents a hypothesis which contends that the development of organismic complexity in the eukaryotes depended extensively on propagation via flagellated and ciliated gametes. Organisms utilizing flagellate and ciliate gametes to propagate their germ line have contributed most of the organismic complexity found in the higher animals. The genes of the flagellum and the flagellar assembly system (intraflagellar transport) have played a disproportionately important role in the construction of complex tissues and organs. The hypothesis also proposes that competition between (...) large numbers of haploid flagellated male gametes rigorously conserved the functionality of a key set of flagellar genes for more than 700 million years. This in turn has insured that a large set (>600) of highly functional cytoskeletal and signal pathway genes is always present in the lineage of organisms with flagellated or ciliated gametes to act as a dependable resource, or “toolkit,” for organ elaboration. Also see the video abstract here: https://youtu.be/lC5nC-WOcm8. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Is Oedipus Smart?Charles B. DanielsWhat does it amount to, to ask whether Oedipus is smart, intelligent, clever? I take this to mean that he is quicker than most to gain understanding about difficult matters. Now, does Sophocles in Oedipus Rex portray Oedipus to be an intelligent, clever man?The Yes AnswerA "yes" answer to the title question may rest upon three grounds:Y1. Everyone in the play, including Oedipus himself (...) and the citizens of Thebes who have been his subjects for some 15 to 20 years, everyone, that is, save Teiresias, thinks that Oedipus is intelligent.Y2. In both legend and Sophocles' play, the only person smart enough to solve the Sphinx's riddle is Oedipus. Everyone in the play, as well as in the play's audiences, knows that Oedipus has solved the Sphinx's riddle. This is a major reason why everyone in the play, again excepting Teiresias, believes Oedipus to have a first-class mind. Oedipus is renown for this deed and thought by his subjects to be very clever in doing of it.Y3. John P. Carroll, in his interesting study of the extraordinary number of questions posed by Oedipus in Oedipus Rex (one in each nine lines of text uttered by him), concludes, "King Oedipus was endowed at birth with the heritage of the 'riddler's mind,' which by constant use throughout the course of his life he sharpened and brought to greater [End Page 562] perfection than it ever had had in his parents." 1 Oedipus is clever because he has a "riddler's mind": he asks lots of questions.Y1, Y2, and Y3, I believe, constitute the sole evidential textual base for the "yes" response to the title question. 2The No AnswerThe "no" answer, the view that Oedipus is not clever, rests upon four grounds:N1. The first consists of events from Oedipus' past that took place prior to the opening scene of the play and hence do not occur on stage. These are disclosed as the play progresses and its characters relate in dialogue what they believe to have taken place. We discover that Oedipus has lived his entire adult life with unresolved doubts about who his parents are. Worse yet, at the very beginning of his adult life, his inquiry at the Delphic Oracle met with terrible, enigmatic pronouncements that raised the ante on these doubts and made the tenor of his whole subsequent life up to the present worrisome to say the least. We learn of six questions of high moment to Oedipus—questions that touch him as profoundly as did the Sphinx's riddle, "What walks on two, three, and four legs?"—questions which he continues to be aware of and yet has not resolved, or in some cases even probed. A truly clever person, one with a "riddler's mind," would have done so. But the mature Oedipus we meet at the beginning of the play has yet to puzzle out correct answers to the questions:1. Where did the scars on my feet come from?2. Who are my real parents, Polybus and Merope, or some other couple?3. How can I best avoid doing the terrible things the Oracle foretells I shall do—killing my father and marrying my mother—given I am not sure who my father and mother really are?4. Is this old man who has just forced me off the road and arrogantly swatted me from his passing carriage my father?5. Who killed the king whose throne I have just been given?6. Is this widow I am about to marry my mother?The Oedipus we see at the beginning of the play is a man who has solved the riddle of the Sphinx, but has not solved a single one of these six questions from his own past life, which, it turns out, are easily of comparable importance to him. [End Page 563]N2. Another source of evidence in support of a "no" answer consists of failures on Oedipus' part to evince a quick wit concerning two puzzles that arise in the dramatic present among the events we see unfold on stage:7. The riddles... (shrink)

Arguably the most influential of all contemporary English-speaking philosophers, Richard Rorty has transformed the way many inside and outside philosophy think about the discipline and the traditional ways of practising it. Drawing on a wide range of thinkers from Darwin and James to Quine, Wittgenstein, Heidegger and Derrida, Rorty has injected a bold anti-foundationalist vision into philosophical debate, into discussions in literary theory, communication studies, political theory and education, and, as public intellectual, into national debates about the responsibilities of America (...) in the modern world. The essays in this volume offer a balanced exposition and critique of Rorty's views on knowledge, language, truth, science, morality and politics. The editorial introduction presents a valuable overview of Rorty's philosophical vision. Written by a distinguished team of philosophers, this volume will have an unusual appeal outside philosophy to students in the social sciences, literary studies, cultural studies and political theory. (shrink)

In a 1994 ANALYSIS article Peter Klein and Ted Warfield show that an epistemically more coherent set of beliefs often has a smaller unconditional probability of joint truth than some of its less coherent subsets. They conclude that epistemic justification, as understood in one version of a coherence theory of justification, is not truth conducive. After getting clear about what truth conduciveness requires, I show that their argument does not tell against BonJour's coherence theory.

Stone & Wang collate the nascent research examining the mnemonic consequences associated with social media use. In particular, they highlight two important factors in understanding how social media use shapes the way individuals and groups remember the past: the type of information (personal vs. public) and the role (producer vs. consumer) individuals undertake when engaging with social media. Stone and Wang investigate those two features in relation to induced forgetting for personal information and false memories/truthiness for public information.

This paper examines the characteristics of infectious diseases that raise special medical and social ethical issues, and explores ways of integrating both current bioethical and classical public health ethics concerns. Many of the ethical issues raised by infectious diseases are related to these diseases’ powerful ability to engender fear in individuals and panic in populations. We address the association of some infectious diseases with high morbidity and mortality rates, the sense that infectious diseases are caused by invasion or attack on (...) humans by foreign micro‐organisms, the acute onset and rapid course of many infectious diseases, and, in particular, the communicability of infectious diseases. The individual fear and community panic associated with infectious diseases often leads to rapid, emotionally driven decision making about public health policies needed to protect the community that may be in conflict with current bioethical principles regarding the care of individual patients. The discussion includes recent examples where dialogue between public health practitioners and medical‐ethicists has helped resolve ethical issues that require us to consider the infected patient as both a victim with individual needs and rights and as a potential vector of disease that is of concern to the community. (shrink)

We propose a model of physics that blends Rovelli’s relational quantum mechanics (RQM) interpretation with the language of finite information quantities (FIQs), defined by Gisin and Del Santo in the spirit of intuitionistic mathematics. We discuss deficiencies of using real numbers to model physical systems in general, and particularly under the RQM interpretation. With this motivation for an alternative mathematical language, we propose the use of FIQs to model the world under the RQM interpretation, wherein we view the propensities that (...) make up a FIQ as quantifications of potential interaction. Under this model, the stable facts, relative facts, and shifting perspectives that make up the relational interpretation correspond to shifting digits and propensities of the FIQs. The model’s predictions agree with those of both classical and quantum physics, and it is indeterministic. We also propose explanations, with examples, for how the propensities of a FIQ are distributed, and how its digits become actualized. This is equivalent to the notion of the measurement problem, and the question of what causes wave function collapse. In short, by stepping through the “new door” opened by the language of FIQs, we attempt to describe the world under the relational interpretation. (shrink)

Temporal necessity and the subjunctive conditional appear to be related by the principle of Past Predominance, according to which past similarities and differences take priority over future similarities and differences in determining the comparative similarity of alternative possible histories with respect to the present moment. R. H. Thomason and Anil Gupta have formalized Past Predominance in a semantics that combines selection functions with branching time; in this paper I show that Past Predominance can be formalized and axiomatized using ordinary possible (...) worlds semantics (without branching time). (shrink)

As originally planned this volume was meant to cover a somewhat wider scope than, in fact, it has turned out to do. When, in rg68, I initially conceived of preparing it, it was proposed to deal with several aspects of early modern scepticism, in addition to the fortuna of the Academica, and to publish various loosely related pieces under the title of 'Studies in the History of Early Modern Scepticism. ' Thereby, I foresaw that I would exhaust my knowledge of (...) the subject and would then be able to turn my attention to other matters. In initiating my research on this topic, however, I soon found that there remained a much greater bulk of material to study than could possibly be dealt with between the covers of the single modest volume which I envisioned. My proposed section on Cicero's Academica was to cover between 50 and 75 pages in the original plan. It soon became apparent, however, especially after Joannes Rosa's hitherto unstudied commentary on Cicero's work was uncovered, that this material would have to be treated at a much greater length than I had foreseen. The present volume is the result of this expanded investigation. The monograph which has come from this alteration in plans has, I think, the virtues of continuity and cohesive ness and one hopes that these advantages offset the benefits of a broader scope which were sacrificed. (shrink)

Three views on definite descriptions are summarized and discussed, including that of P. F. Strawson in which reference failure results in lack of truth value. When reference failure is allowed, a problem arises concerning Universal Instantiation. Van Fraassen solves the problem by the use of supervaluations, preserving as well such theorems as a=a, and Fa or ~Fa, even when the term a fails to refer. In the present paper a form of relevant, quasi-analytic implication is set out which allows reference (...) failure to infect even a=a and Fa or ~Fa with lack of truth-value. Reference failure causes lack of truth-value in a subwff to spread throughout any wff built up by the classical connectives. As a result none of the classical first-order axiom schemes remain as axiom schemes in the system presented. (shrink)

In “Backward Causation and the Stalnaker–Lewis Approach to Counterfactuals,” Analysis 62:191–7, (2002), Michael Tooley argues that if a certain kind of backward causation is possible, then a Stalnaker–Lewis comparative world similarity account of the truth conditions of counterfactuals cannot be sound. In “Tooley on Backward Causation,” Analysis 63:157–62, (2003), Paul Noordhof argues that Tooley’s example can be reconciled with a Stalnaker–Lewis account of counterfactuals if the comparative world similarity relation on which the Stalnaker–Lewis account relies is allowed to be antecedent-relative. (...) In this paper I show that taking comparative world similarity to be antecedent-relative results in a formal semantics which is a comparative world similarity semantics in name only. (shrink)

In this essay I renew the case for Conditional Excluded Middle in light of recent developments in the semantics of the subjunctive conditional. I argue that Michael Tooley's recent backward causation counterexample to the Stalnaker-Lewis comparative world similarity semantics undermines the strongest argument against CXM, and I offer a new, principled argument for the validity of CXM that is in no way undermined by Tooley's counterexample. Finally, I formulate a simple semantics for the subjunctive conditional that is consistent with both (...) CXM and Tooley's counterexample. (shrink)

John Case , the most important English Aristotelian of the Renaissance period, has not yet received the attention he deserves. In his Lapis philosophicus , an exposition of Aristotle's Physics, is found a discussion of the relation of nature to art which parallels in many ways that formulated a few years later in the writings of Francis Bacon. Case argues, in a way more reminiscent of the works of Giambattista della Porta than of those of Aristotle, that the natural philosopher (...) can legitimately apply the productive arts in helping nature to fulfill her function. Moreover, while rejecting the excessive claims of the Paracelsians, Case does accept the transmutational claims of the alchemists. In the final analysis, his ‘Aristotelianism’ has been tempered by the tradition of Renaissance natural magic. Like many other Peripatetic thinkers of the period, Case shows himself to be an eclectic, drawing materials from a wide variety of sources and open to many of the new scientific tendencies then developing. (shrink)

The origins of this book go back to I956 when it was suggested to me that a study on the philosophy of Gianfrancesco Pico della Mirandola would furnish an important addition to our knowledge of the philoso phy of the Italian Renaissance. It was not, however, until I960 that I could devote a significant portion of my time to a realization of this goal. My work was essentially completed in 1963, at which time it was presented in its original form (...) as a doctoral dissertation in the Phi losophy Department of Columbia University. Since then I have made many minor improvements and several chapters have been extensively reworked. This study represents the first attempt in fifty years to give a detailed account of even a portion of Gianfrancesco Pico's life and thought. The most comprehensive previous study, Gertrude Bramlette Richards, "Gianfrancesco Pico della lv1irandola" (Cornell University Dissertation, I 9 I 5), which I have found very useful in preparing my own book, is largely based on secondary literature and is mistaken in a number of details. Furthermore, Miss Richards' treatment of Gian francesco Pico as a thinker is very sketchy and is not an exhaustive study of his own writings. It is hoped that my present study, built in part on her extensive bibliographical indications, brings forth a certain amount of new information which will be of value for further research. (shrink)

In "Against the Indicative," AUSTRALASIAN JOURNAL OF PHILOSOPHY 72 (1994): 17-26, and more recently in "Classifying `Conditionals': the Traditional Way is Wrong", ANALYSIS 60 (2000): 147, V.H. Dudman argues that (a) `If Oswald didn't shoot Kennedy then someone else did' and (b) `If Oswald doesn't shoot Kennedy then someone else will' should not be classified together as "indicative conditionals." Dudman relies on the assumption that (a) is entailed by (c) `Someone shot Kennedy', whereas (b) is not entailed by (d) `Someone (...) will shoot Kennedy'. I argue that the same reasoning which shows that (d) does not entail (b) also shows that (c) does not entail (a). One upshot is that Dudman's and Mellor's respective interpretations of so-called past indicative conditionals cannot be correct. (shrink)

Introduction: the ways and means of cultural change -- Science, industry and the invention of a new worldview -- Management as cultural authority -- The cultural values of work and leisure -- The strategy & spirit of capitalism -- From material need to consumer culture -- Higher learning as marketplace -- Globalization of the tightening systems knot -- Time to think -- Balancing values through cultural change -- Progress and myth -- Knowledge devalued: summary & conclusions.

A selection function based semantics is offered for the 'can' of ability based on the idea that 'John can run a four minute mile' is true iff John would do so under the right conditions, meaning that he would do so under at least one appropriately chosen test condition. Completeness is proved for an axiom system and semantics based on this idea, and the logic turns out to be interestingly different from any standard system of modal logic.

Nonmonotonic consequence is the subject of a vast literature, but the idea of a nonmonotonic counterpart of logical inconsistency—the idea of a defeasible property representing internal conflict of an inductive or evidential nature—has been entirely neglected. After considering and dismissing two possible analyses relating nonmonotonic consequence and a nonmonotonic counterpart of logical inconsistency, this paper offers a set of postulates for nonmonotonic inconsistency, an analysis of nonmonotonic inconsistency in terms of nonmonotonic consequence, and a series of results showing that nonmonotonic (...) inconsistency conforms to these postulates given the analysis of nonmonotonic inconsistency presented here and certain postulates for nonmonotonic consequence. The results presented here establish the interest of certain previously undiscussed postulates of nonmonotonic consequence. These results also show that nonmonotonicity, which has never seemed useful in the formulation of general principles governing nonmonotonic reasoning, is relevant to the positive characterization of nonmonotonic inference after all. (shrink)

Despite the results of David Lewis, Peter Gärdenfors, and others, showing that imaging and classical conditionalization coincide only in the most trivial probabilistic models of belief revision, it turns out that imaging on a proposition A can always be described via Popper function conditionalization on a proposition that entails A. This result generalizes to any method of belief revision meeting certain minimal requirements. The proof is illustrated by an application of imaging in the context of the Monty Hall Problem.

In lieu of an abstract, here is a brief excerpt of the content:Giulio Castellani (1528-1586): A Sixteenth-Century Opponent of Scepticism CHARLES B. SCH1VHTT THE PROBLEMOF THE ORIGINS of scepticism in early modern philosophy has been a much debated issue. Sanches, Montaigne, Charron, and Bayle all contributed to the milieu which made it possible for the sceptical direction of thought to develop into such a potent force by the time of David Hume. The actual origins of modern scepticism, which seem (...) to go back to a slightly earlier date, lie in the confluence of several different intellectual movements during the early years of the sixteenth century: Christian anti-intellectualism, the reintroduction of the literary remains of the ancient sceptical tradition, the epistemological developments of scholastic nominalism, and certain inherent tendencies of Renaissance humanism. It is in the early decades of the sixteenth century that the seeds which later blossomed forth at the time of Hume originally took root. Hume himself merely reaped the harvest of several hundred years of sceptical preparation? Aside from certain manifestations of doubt which developed out of the epistemological theories of fourteenth-century nominalism, the origins of modern scepticism are generally held to date from the first publication of Sextus Empiricus' ancient summaries of Pyrrhonism during the decade of the 1560's. While it has previously been recognized that at least hints of scepticism were current in the fifteenth and early sixteenth centuries, the implications to be derived from this fact do not seem to have been adequately exploredT I shall not here go into these early manifestations of scepticism in a detailed way. Rather, I shall briefly touch upon a few little-known examples of the influence of ancient scepticism during the Reniassance and, then, I shall focus upon an early and practically neglected attack upon scepticism published before the first printings of Sextus Empiricus' writings. I shall discuss the circumstances of the composition of Giulio Castellani's anti-sceptical work, Adversus Marci TuIlii Ciceronis academicas questiones disi For a recent survey of early modem scepticism see Richard H. Popkin, The History o] Scepticism /tom Erasmus to Descartes (Assen: 1960). Of the large literature which connects scepticism with religious doubt during this period see especially Henri Busson, Les sources et le dgveloppement du rati~nalizme dar~ la litt~rature ]ran~aise de la Renaissance (Paris: 1957) and Don Cameron Allen, Doubt's Boundless Sea (Baltimore: 1964). The di.~cussionof this period seems to be the weakest part of Popkin's excellent book, particularly with regard to the treatment which he gives to Italian thought. See, also, his other articles, especially,"Skepticismand the Counter-Reformation in France," Archiv/fir Re/armationsgeschichte, LI (1960),58-86and "The High Road to Pyrrhonism," American Philosophical Quarterly, II (1965),18--32.In my forthcoming study, Gian]rancesco Pico (1469-1533) and His Critique o/Aristotle, I give a detailed analysis of the major representative of early sixteenthcentury scepticism. [151 16 HISTORY OF PHILOSOPHY putatio (1558), which antedates the first printing of Sextus Empiricus by four years, indicating that scepticism was already widespread enough to provoke an attack from the camp of the dogmatists. Furthermore, I shall analyze Castellani 's arguments in the context of the philosophical views of the mid-sixteenth century. Scepticism in the Early Renaissance Direct knowledge of the major ancient source of scepticism, the already mentioned writings of Sextus Empiricus, was rare throughout the Middle Ages. There are but two known extant Latin manuscripts which date before 1400. s From the fifteenth century we know of two more manuscripts, neither complete in itself, but together containing a significant portion of the extant writings of Sextus. 4 This evidence indicates that Sextus' works were not well known in translation before the first Latin editions of The Oulines o] Pyrrhonism (1562) and of Against the Mathematicians (1569). With the advent of an increased interest in and knowledge of Greek in Western Europe in the fifteenth century, we find a corresponding increase in the number of Greek manuscripts of Sextus Empiricus. Consequently, by the time of the first printings, an appreciable number of copies of his writings were available. Some were brought from the East, but a large number also are attributable to European scribes. 5 We also know that in... (shrink)

In this essay I present a new version of the Paradox of the Knower and show that this new paradox vitiates a certain argument against epistemic closure. I then prove a theorem that relates the new paradox to epistemological scepticism. I conclude by assessing the use of the Knower in arguments against syntactical treatments of knowledge.

In The Scientific Image B. C. van Fraassen argues that a theory of explanation ought to take the form of a theory of why-questions, and a theory of this form is what he provides. Van Fraassen's account of explanation is good, as far as it goes. In particular, van Fraassen's theory of why-questions adds considerable illumination to the problem of alternative explanations in psychodynamics. But van Fraassen's theory is incomplete because it ignores those classes of explanations that are answers not (...) to why-questions but to how-questions. In this article I provide a unified theory of explanatory questions that comprehends both how-questions and why-questions, and I show that a question-theoretic approach to explanation can be defended independently of van Fraassen's programme of Constructive Empiricism. (shrink)

"An invaluable source for undergraduate courses in continental philosophy." --Giovanna Borradori, Vassar College.

The United States Supreme Court's decision in Bell Atlantic Corp. v. Twombly is creating quite a stir. Suddenly gone is the famous loosey-goosey rule of Conley v. Gibson that a complaint should not be dismissed for failure to state a claim unless it appears beyond doubt that the plaintiff can prove no set of facts in support of his claim which would entitle him to relief.Now a complaint must provide enough facts to state a claim to relief that is plausible (...) on its face. Only decided last May, Bell Atlantic has been cited in over 3,700 cases. Already being described as a landmark decision, Bell Atlantic nonetheless has lawyers and judges scratching their heads over the precise pleading standard to apply in its wake. As the Second Circuit (mildly) put it, Considerable uncertainty concerning the standard for assessing the adequacy of pleadings has recently been created by the Supreme Court's decision in Bell Atlantic Corp. v. Twombly. Just what is a plausible showing that the pleader is entitled to relief under Rule 8(a)(2)?I believe an answer lies in the 26-year-old decision of the Former Fifth Circuit in In re Plywood Antitrust Litigation. Plywood Antitrust requires, at a minimum, that a complaint . . . contain either direct or inferential allegations respecting all the material elements necessary to sustain a recovery under some viable legal theory. Already used in more than half the circuits, this standard paraphrases advice found in the venerable WRIGHT & MILLER for nearly 40 years.Properly applied, this all . . . material elements standard satisfies Bell Atlantic's plausibility requirement in all respects. The Plywood Antitrust pleading standard works well after Bell Atlantic, first, because the Supreme Court referred to the standard, albeit parenthetically, with approval in Bell Atlantic. Second, it does much to harmonize the Federal Rules' goal of dispensing with pleading technicalities while still requiring enough general factual information about a pleader's claim to make the notice in notice pleading meaningful. Finally, and perhaps most importantly, it gives lawyers, litigants, and courts a standard they can actually use when drafting, or assessing the sufficiency of, pleadings. (shrink)

An exploration of the importance of the arts to business in this time of structural transformation. The work argues that businesses will only be successful if people are in them for the love of the game, as they are in the arts. Handy is the author of The Age of Unreason and The Empty Raincoat.

I give a probabilistic semantics for modal logic in which modal operators function as quantifiers over Popper functions in probabilistic model sets, thereby generalizing Kripke's semantics for modal logic.